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Xilio Therapeutics, Inc. is projected to rise to $10.81 by 2027, a +19% move from its current price of $9.10. XLO is currently trading above its 50-day average (a bullish sign). Technical indicators currently lean buy.
A data-driven summary — not financial advice. See the full breakdown below.
Live market data via Yahoo Finance · updated 7/12/2026
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Jul 13 | $8.92 | $9.11 | $9.31 | +0.10% |
| Jul 14 | $8.85 | $9.12 | $9.40 | +0.20% |
| Jul 15 | $8.79 | $9.13 | $9.47 | +0.31% |
| Jul 16 | $8.75 | $9.14 | $9.54 | +0.41% |
| Jul 17 | $8.72 | $9.15 | $9.60 | +0.51% |
| Jul 18 | $8.69 | $9.16 | $9.65 | +0.61% |
| Jul 19 | $8.66 | $9.17 | $9.70 | +0.72% |
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Week 1 | $8.66 | $9.17 | $9.70 | +0.72% |
| Week 2 | $8.52 | $9.23 | $10.00 | +1.44% |
| Week 3 | $8.43 | $9.30 | $10.26 | +2.16% |
| Week 4 | $8.36 | $9.36 | $10.49 | +2.90% |
| Week 5 | $8.30 | $9.43 | $10.71 | +3.63% |
| Week 6 | $8.26 | $9.50 | $10.92 | +4.37% |
| Week 7 | $8.23 | $9.57 | $11.12 | +5.12% |
Short-term targets derived from the forecast trend and recent volatility. Highly uncertain — not financial advice.
Xilio Therapeutics, Inc. is a clinical-stage biotechnology company that focuses on the discovery and development of masked immuno-oncology therapies.
Its pipeline includes XTX501, a bispecific PD-1 / masked IL-2, for patients with metastatic non-small cell lung cancer; Efarindodekin alfa, an investigational, masked IL-12, that is in Phase 2 clinical trial for patients with advanced solid tumors; and Vilastobart, an investigational tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4 monoclonal antibody.
The company was founded in 2016 and is headquartered in Waltham, Massachusetts.
XLO is trading at $8.94 with a market cap of $57.8M and a rank 5456.
The near-term forecast places 2026 with an average price of $8.94, ROI 0, and sentiment NEUTRAL.
Looking further, the forecast shows a bullish trajectory with the average price rising to $12.32 by 2030 and to $58.01 by 2050, with ROIs of 37.9 and 548.9 respectively. The 2040 forecast shows an average price of $34.35 and ROI 284.3.
The forecast spans 2026 through 2050 and suggests sustained upside potential across multiple years.
A major floor 24.3% below — a decisive break under it would weaken the trend.
The nearest floor, 15.6% below — buyers have tended to step in here.
The nearest ceiling, 5.3% above — a clean break opens room to run.
A major ceiling 17.4% above — clearing it would confirm fresh momentum.
Key XLO support and resistance from recent price action — levels where the trend has historically paused or reversed. Percentages are the distance from the current price.
A snapshot of XLO market posture derived from its technical indicators and recent volatility. Higher trend and alignment lean bullish; higher risk means larger swings.
Technical Analysis
Indicators computed on daily closing prices.
| Period | SMA | Action | EMA | Action |
|---|---|---|---|---|
| MA 5 | $9.27 | Sell | $9.20 | Sell |
| MA 10 | $9.26 | Sell | $9.16 | Sell |
| MA 20 | $8.94 | Buy | $8.97 | Buy |
| MA 50 | $8.44 | Buy | $8.64 | Buy |
| MA 100 | $8.23 | Buy | $8.59 | Buy |
| MA 200 | $9.11 | Sell | $9.04 | Buy |
| Name | Value | Action |
|---|---|---|
| RSI (14) | 55.86 | Neutral |
| Stoch RSI (14) | 0.00 | Buy |
| CCI (20) | 32.75 | Neutral |
| Williams %R (14) | -69.57 | Info |
| MACD (12,26,9) | -0.00 | Sell |
| ROC (12) | 2.25 | Buy |
| Bollinger %B (20,2) | 0.60 | Neutral |
| Stochastic %K (14) | 30.43 | Neutral |
| TRIX (15) | 0.45 | Buy |
| Awesome (5,34) | 0.64 | Buy |
| Ultimate (7,14,28) | 40.10 | Neutral |
| Momentum (10) | 0.21 | Buy |
| Aroon Osc (25) | 60.00 | Buy |
| Hull MA (9) | 9.20 | Sell |
| ADX (14) | 19.78 | Neutral |
| ATR (14) | 0.16 | Info |
The 30-day technical picture for XLO is BULLISH. RSI14 is 60, SMA50 is $8.24, and SMA200 is $9.19.
Support is $7.68 and resistance is $8.94, with a 30-day range from $7.51 to $10.64.
| Year | Min | Avg | Max | ROI | Sentiment |
|---|---|---|---|---|---|
| $7.14 | $9.10 | $12.90 | 0% | Neutral | |
| $8.78 | $10.81 | $13.98 | +19% | Neutral | |
| $9.59 | $12.07 | $16.08 | +33% | Bullish | |
| $10.37 | $13.28 | $18.12 | +46% | Bullish | |
| $10.07 | $13.10 | $18.22 | +44% | Bullish | |
| $11.22 | $14.81 | $20.97 | +63% | Bullish | |
| $13.19 | $17.63 | $25.36 | +94% | Bullish | |
| $14.75 | $19.96 | $29.13 | +119% | Bullish | |
| $15.98 | $21.87 | $32.34 | +140% | Bullish | |
| $16.02 | $22.17 | $33.18 | +144% | Bullish | |
| $23.57 | $34.27 | $54.02 | +277% | Bullish | |
| $39.18 | $61.89 | $105.31 | +580% | Bullish |
Current year — the forecast is anchored to the live price, so ROI shows 0%.
| Month | Min | Avg | Max | Change |
|---|---|---|---|---|
| July 2026 | $7.14 | $9.10 | $11.03 | +0.00% |
| August 2026 | $8.35 | $9.80 | $11.76 | +7.65% |
| September 2026 | $8.46 | $9.99 | $12.10 | +1.94% |
| October 2026 | $8.42 | $9.98 | $12.18 | -0.10% |
| November 2026 | $8.58 | $10.22 | $12.55 | +2.39% |
| December 2026 | $8.74 | $10.44 | $12.90 | +2.22% |
Click any year to see its month-by-month XLO forecast. Min / Avg / Max are a bear / base / bull scenario; ROI is the projected move from the current price. Change is the month-over-month move in the average. Estimates, not guarantees.
By 2026, XLO could reach as high as $12.90, with a base case around $9.10 and support toward $7.14 — roughly 0% from $9.10. Price action looks broadly range-bound.
Expect XLO to range from $8.78 to $13.98 through 2027. The $10.81 average target implies a +19% move from current prices. That is up +19% on the projected 2026 average. A consolidation phase looks the most probable path here.
The XLO price prediction for 2028 points to an average of $12.07 (low $9.59, high $16.08) — a potential gain of +33% on today's $9.10. Momentum favours further upside here.
In 2029, XLO is projected to trade between $10.37 and $18.12, averaging $13.28 — a potential gain of +46% from today's $9.10. That is up +10% on the projected 2028 average. Buyers look set to stay in control over this stretch.
Xilio Therapeutics, Inc.'s 2030 outlook centres on $13.10, within a $10.07 to $18.22 range. That is -1% versus the projected 2029 average. That marks a +44% change versus current levels. Momentum favours further upside here.
By 2031, XLO could reach as high as $20.97, with a base case around $14.81 and support toward $11.22 — roughly +63% from $9.10. Buyers look set to stay in control over this stretch.
Expect XLO to range from $13.19 to $25.36 through 2032. The $17.63 average target implies a +94% move from current prices. That is up +19% on the projected 2031 average. Momentum favours further upside here.
The XLO price prediction for 2033 points to an average of $19.96 (low $14.75, high $29.13) — a potential gain of +119% on today's $9.10. Buyers look set to stay in control over this stretch.
In 2034, XLO is projected to trade between $15.98 and $32.34, averaging $21.87 — a potential gain of +140% from today's $9.10. That is up +10% on the projected 2033 average. Momentum favours further upside here.
Xilio Therapeutics, Inc.'s 2035 outlook centres on $22.17, within a $16.02 to $33.18 range. That is up +1% on the projected 2034 average. That marks a +144% change versus current levels. Buyers look set to stay in control over this stretch.
By 2040, XLO could reach as high as $54.02, with a base case around $34.27 and support toward $23.57 — roughly +277% from $9.10. Momentum favours further upside here.
Expect XLO to range from $39.18 to $105.31 through 2050. The $61.89 average target implies a +580% move from current prices. That is up +81% on the projected 2040 average. Buyers look set to stay in control over this stretch.
Investing $1,000 in XLO today (≈ 109.89011 XLO) could be worth
$6,800.8
+$5,800.8 (+580%) by 2050 · US Dollar
Based on the average projected XLO price of $61.89 in 2050.
Based on the base (average) forecast scenario. FX rates are indicative. Estimates only — not financial advice.
See what a past investment in XLOwould be worth at today's price.
$1,000 invested in XLO on Jul 10, 2025 (≈ 96.006141 XLO) would be worth
$873.66
-$126.34 (-12.6%) today · 0.87× · US Dollar
Based on a XLO entry price of $10.42 vs. today's $9.1.
| Invested | Entry price | Value today | Return |
|---|---|---|---|
| 1 week ago | $9.15 | $994.54 | -0.5% |
| 1 month ago | $7.9 | $1,151.9 | +15.2% |
| 3 months ago | $8.51 | $1,069.33 | +6.9% |
| 6 months ago | $9.34 | $974.51 | -2.5% |
| 1 year ago | $10.42 | $873.66 | -12.6% |
| All time (4.7y) ago | $224 | $40.63 | -95.9% |
Past performance from historical market data — it does not predict future results. FX rates are indicative. Not financial advice.
Enter a price to see how it sits against our XLO forecast.
Our base-case forecast reaches $18.00 around 2033.
Implied market cap at $18.00: $118.35M
From a multi-year perspective, the forecast shows a bullish path with 2027 avg $10.63, 2028 avg $12.09, and 2029 avg $12.88.
By 2030 the avg is $12.32 with ROI 37.9; by 2031 avg $14.53 (ROI 62.5), by 2032 avg $17.26 (ROI 93), by 2033 avg $19.41 (ROI 117.1), by 2034 avg $21.71 (ROI 142.8), by 2035 avg $21.26 (ROI 137.8).
Further out, 2040 avg $34.35 (ROI 284.3) and 2050 avg $58.01 (ROI 548.9), with bullish sentiment.
Tap a question to reveal the answer.
Avg price $12.32; Min $9.18; Max $17.82; ROI 37.9; sentiment BULLISH.
Forecasts show positive long-term momentum with higher averages in later years; for example, 2031 avg $14.53; 2032 avg $17.26; 2040 avg $34.35; 2050 avg $58.01. These are estimates, not guarantees.
Yes—the 2050 max forecast is $105.88, and the 2050 avg is $58.01, so $50 is within the projected range.
Current price $8.94 and market cap $57.8M.
Avg $10.63; Min $8.47; Max $14.09; ROI 18.9; sentiment NEUTRAL.
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