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Xilio Therapeutics, Inc. is projected to rise to $10.04 by 2027, a +20% move from its current price of $8.34. XLO is currently trading above its 50-day average (a bullish sign). Technical indicators currently lean strong buy.
A data-driven summary — not financial advice. See the full breakdown below.
Live market data via Yahoo Finance · updated 5/28/2026
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| May 29 | $8.11 | $8.35 | $8.60 | +0.12% |
| May 30 | $8.02 | $8.36 | $8.72 | +0.24% |
| May 31 | $7.95 | $8.37 | $8.81 | +0.36% |
| Jun 1 | $7.90 | $8.38 | $8.89 | +0.48% |
| Jun 2 | $7.85 | $8.39 | $8.97 | +0.60% |
| Jun 3 | $7.81 | $8.40 | $9.03 | +0.72% |
| Jun 4 | $7.78 | $8.41 | $9.10 | +0.84% |
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Week 1 | $7.78 | $8.41 | $9.10 | +0.84% |
| Week 2 | $7.59 | $8.48 | $9.48 | +1.69% |
| Week 3 | $7.46 | $8.55 | $9.80 | +2.55% |
| Week 4 | $7.37 | $8.62 | $10.09 | +3.41% |
| Week 5 | $7.30 | $8.70 | $10.37 | +4.28% |
| Week 6 | $7.24 | $8.77 | $10.63 | +5.16% |
| Week 7 | $7.18 | $8.84 | $10.89 | +6.05% |
Short-term targets derived from the forecast trend and recent volatility. Highly uncertain — not financial advice.
Xilio Therapeutics, Inc. is a clinical-stage biotechnology company focused on discovery and development of masked immuno-oncology therapies.
Its pipeline includes XTX501, a bispecific PD-1 / masked IL-2, for patients with metastatic non-small cell lung cancer; Efarindodekin alfa, an investigational, masked IL-12, that is in Phase 2 clinical trial for patients with advanced solid tumors; and Vilastobart, an investigational tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4 monoclonal antibody.
The company was founded in 2016 and is headquartered in Waltham, Massachusetts.
Xilio Therapeutics, Inc. trades under the symbol XLO and is currently priced at $8.25 per share with a market cap of $49.36M. It is ranked 4602 in market capitalization.
The current price sits near notable moving averages, with a SMA50 of $8.19 and a SMA200 of $9.32. The stock shows a 30-day range from $6.71 to $10.15, with a nearby support level at $7.71 and a resistance at $8.81.
Forecasts indicate a neutral setup for 2026 with an average price of $8.25 and ROI of 0, followed by a bullish trajectory into 2030 and beyond. Notable long-horizon targets include a 2040 average of $23.95 and a 2050 average of $36.24, with corresponding max values and rising sentiment.
A major floor 14.4% below — a decisive break under it would weaken the trend.
The nearest floor, 7.6% below — buyers have tended to step in here.
The nearest ceiling, 5.6% above — a clean break opens room to run.
A major ceiling 12.5% above — clearing it would confirm fresh momentum.
Key XLO support and resistance from recent price action — levels where the trend has historically paused or reversed. Percentages are the distance from the current price.
A snapshot of XLO market posture derived from its technical indicators and recent volatility. Higher trend and alignment lean bullish; higher risk means larger swings.
Technical Analysis
Indicators computed on daily closing prices.
| Period | SMA | Action | EMA | Action |
|---|---|---|---|---|
| MA 5 | $8.39 | Sell | $8.34 | Buy |
| MA 10 | $8.32 | Buy | $8.28 | Buy |
| MA 20 | $8.11 | Buy | $8.22 | Buy |
| MA 50 | $8.23 | Buy | $8.21 | Buy |
| MA 100 | $8.22 | Buy | $8.46 | Sell |
| MA 200 | $9.31 | Sell | $9.15 | Sell |
| Name | Value | Action |
|---|---|---|
| RSI (14) | 52.60 | Neutral |
| Stoch RSI (14) | 52.18 | Neutral |
| CCI (20) | 52.97 | Neutral |
| Williams %R (14) | -43.52 | Info |
| MACD (12,26,9) | 0.04 | Buy |
| ROC (12) | 7.75 | Buy |
| Bollinger %B (20,2) | 0.68 | Neutral |
| Stochastic %K (14) | 56.48 | Neutral |
| TRIX (15) | 0.00 | Buy |
| Awesome (5,34) | 0.15 | Buy |
| Ultimate (7,14,28) | 51.72 | Neutral |
| Momentum (10) | 0.61 | Buy |
| Aroon Osc (25) | 28.00 | Buy |
| Hull MA (9) | 8.37 | Sell |
| ADX (14) | 11.05 | Neutral |
| ATR (14) | 0.19 | Info |
The 30-day technical picture is bullish with a neutral RSI around 50, reflecting balanced momentum.
Price action sits just above the SMA50 ($8.19) and below the SMA200 ($9.32), suggesting near-term consolidation near the 50-day average.
Support is indicated at $7.71 and resistance at $8.81, while the 30-day trading range spans $6.71 to $10.15.
| Year | Min | Avg | Max | ROI | Sentiment |
|---|---|---|---|---|---|
| $7.14 | $8.34 | $12.09 | 0% | Neutral | |
| $7.89 | $10.04 | $13.56 | +20% | Bullish | |
| $8.24 | $10.79 | $15.15 | +29% | Bullish | |
| $8.04 | $10.79 | $15.62 | +29% | Bullish | |
| $7.51 | $10.32 | $15.32 | +24% | Bullish | |
| $8.34 | $11.69 | $17.74 | +40% | Bullish | |
| $9.38 | $13.39 | $20.74 | +61% | Bullish | |
| $10.57 | $15.37 | $24.24 | +84% | Bullish | |
| $11.39 | $16.86 | $27.03 | +102% | Bullish | |
| $10.66 | $16.03 | $26.11 | +92% | Bullish | |
| $15.51 | $25.13 | $43.68 | +201% | Bullish | |
| $20.89 | $38.56 | $73.66 | +362% | Bullish |
Current year — the forecast is anchored to the live price, so ROI shows 0%.
| Month | Min | Avg | Max | Change |
|---|---|---|---|---|
| May 2026 | $7.14 | $8.34 | $9.83 | +0.00% |
| June 2026 | $7.51 | $8.83 | $10.65 | +5.90% |
| July 2026 | $7.83 | $9.30 | $11.38 | +5.34% |
| August 2026 | $7.78 | $9.30 | $11.51 | -0.04% |
| September 2026 | $7.78 | $9.36 | $11.69 | +0.69% |
| October 2026 | $8.03 | $9.71 | $12.23 | +3.70% |
| November 2026 | $8.00 | $9.72 | $12.33 | +0.12% |
| December 2026 | $7.75 | $9.47 | $12.09 | -2.63% |
Click any year to see its month-by-month XLO forecast. Min / Avg / Max are a bear / base / bull scenario; ROI is the projected move from the current price. Change is the month-over-month move in the average. Estimates, not guarantees.
By 2026, XLO could reach as high as $12.09, with a base case around $8.34 and support toward $7.14 — roughly 0% from $8.34. Price action looks broadly range-bound.
Expect XLO to range from $7.89 to $13.56 through 2027. The $10.04 average target implies a +20% move from current prices. That is up +20% on the projected 2026 average. Buyers look set to stay in control over this stretch.
The XLO price prediction for 2028 points to an average of $10.79 (low $8.24, high $15.15) — a potential gain of +29% on today's $8.34. Momentum favours further upside here.
In 2029, XLO is projected to trade between $8.04 and $15.62, averaging $10.79 — a potential gain of +29% from today's $8.34. That is up 0% on the projected 2028 average. Buyers look set to stay in control over this stretch.
Xilio Therapeutics, Inc.'s 2030 outlook centres on $10.32, within a $7.51 to $15.32 range. That is -4% versus the projected 2029 average. That marks a +24% change versus current levels. Momentum favours further upside here.
By 2031, XLO could reach as high as $17.74, with a base case around $11.69 and support toward $8.34 — roughly +40% from $8.34. Buyers look set to stay in control over this stretch.
Expect XLO to range from $9.38 to $20.74 through 2032. The $13.39 average target implies a +61% move from current prices. That is up +15% on the projected 2031 average. Momentum favours further upside here.
The XLO price prediction for 2033 points to an average of $15.37 (low $10.57, high $24.24) — a potential gain of +84% on today's $8.34. Buyers look set to stay in control over this stretch.
In 2034, XLO is projected to trade between $11.39 and $27.03, averaging $16.86 — a potential gain of +102% from today's $8.34. That is up +10% on the projected 2033 average. Momentum favours further upside here.
Xilio Therapeutics, Inc.'s 2035 outlook centres on $16.03, within a $10.66 to $26.11 range. That is -5% versus the projected 2034 average. That marks a +92% change versus current levels. Buyers look set to stay in control over this stretch.
By 2040, XLO could reach as high as $43.68, with a base case around $25.13 and support toward $15.51 — roughly +201% from $8.34. Momentum favours further upside here.
Expect XLO to range from $20.89 to $73.66 through 2050. The $38.56 average target implies a +362% move from current prices. That is up +53% on the projected 2040 average. Buyers look set to stay in control over this stretch.
Investing $1,000 in XLO today (≈ 119.904077 XLO) could be worth
$4,623.41
+$3,623.41 (+362%) by 2050 · US Dollar
Based on the average projected XLO price of $38.56 in 2050.
Based on the base (average) forecast scenario. FX rates are indicative. Estimates only — not financial advice.
See what a past investment in XLOwould be worth at today's price.
$1,000 invested in XLO on May 27, 2025 (≈ 81.261175 XLO) would be worth
$677.72
-$322.28 (-32.2%) today · 0.68× · US Dollar
Based on a XLO entry price of $12.31 vs. today's $8.34.
| Invested | Entry price | Value today | Return |
|---|---|---|---|
| 1 week ago | $8.44 | $988.15 | -1.2% |
| 1 month ago | $8.18 | $1,019.56 | +2.0% |
| 3 months ago | $7.52 | $1,109.34 | +10.9% |
| 6 months ago | $10.61 | $785.9 | -21.4% |
| 1 year ago | $12.31 | $677.72 | -32.2% |
| All time (4.6y) ago | $224 | $37.23 | -96.3% |
Past performance from historical market data — it does not predict future results. FX rates are indicative. Not financial advice.
Enter a price to see how it sits against our XLO forecast.
Our base-case forecast reaches $17.00 around 2040.
Implied market cap at $17.00: $101.71M
The multi-year forecast shows a bullish trajectory across the horizon, with rising averages and positive sentiment in most years.
Tap a question to reveal the answer.
2030 min $7.22, avg $10.04, max $15.10; ROI 21.7; sentiment BULLISH.
Current price $8.25; market cap $49.36M.
2040 max $42.45 and 2050 max $70.85; 2040 avg $23.95 and 2050 avg $36.24; This indicates potential to exceed $30 by 2040 or 2050.
2040 sentiment BULLISH.
2050 max $70.85.
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