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Pyxis Oncology, Inc. is projected to decline to $1.62 by 2027, a -6% move from its current price of $1.73. PYXS is currently trading below its 50-day average (a bearish sign). Technical indicators currently lean strong sell.
A data-driven summary — not financial advice. See the full breakdown below.
Live market data via Yahoo Finance · updated 5/28/2026
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| May 29 | $1.61 | $1.73 | $1.86 | 0.00% |
| May 30 | $1.56 | $1.73 | $1.91 | -0.01% |
| May 31 | $1.53 | $1.73 | $1.96 | -0.01% |
| Jun 1 | $1.50 | $1.73 | $2.00 | -0.02% |
| Jun 2 | $1.47 | $1.73 | $2.03 | -0.02% |
| Jun 3 | $1.45 | $1.73 | $2.06 | -0.02% |
| Jun 4 | $1.43 | $1.73 | $2.09 | -0.03% |
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Week 1 | $1.43 | $1.73 | $2.09 | -0.03% |
| Week 2 | $1.32 | $1.73 | $2.26 | -0.05% |
| Week 3 | $1.25 | $1.73 | $2.40 | -0.08% |
| Week 4 | $1.18 | $1.73 | $2.52 | -0.11% |
| Week 5 | $1.13 | $1.73 | $2.64 | -0.13% |
| Week 6 | $1.09 | $1.73 | $2.75 | -0.16% |
| Week 7 | $1.05 | $1.73 | $2.85 | -0.19% |
Short-term targets derived from the forecast trend and recent volatility. Highly uncertain — not financial advice.
Pyxis Oncology, Inc. is a healthcare company described as a clinical stage company that develops therapeutics to treat solid tumors. Its lead antibody-drug conjugate candidate is PYX-201, an investigational novel ADC in Phase 1 clinical trial to treat patients with relapsed or refractory solid tumors; PYX-102 is an investigational immunotherapeutic targeting KLRG1, and PYX-106 is an investigational fully human IO product candidate in Phase 1 to treat patients with advanced solid tumors.
Pyxis Oncology, Inc. was incorporated in 2018 and is headquartered in Boston, Massachusetts.
The asset is Pyxis Oncology, Inc. (PYXS), a healthcare stock with current price $1.73 and market capitalization $109.6M, ranking 4141. The current price and market cap place it among smaller-cap healthcare equities.
The long-range outlook shows a path of incremental to substantial gains across the forecast horizon, with average prices rising from $1.73 in 2026 to $2.47 in 2030 and $14.09 in 2050, featuring a wide range of potential outcomes.
A major floor 47.0% below — a decisive break under it would weaken the trend.
The nearest floor, 5.8% below — buyers have tended to step in here.
The nearest ceiling, 59.0% above — a clean break opens room to run.
A major ceiling 82.5% above — clearing it would confirm fresh momentum.
Key PYXS support and resistance from recent price action — levels where the trend has historically paused or reversed. Percentages are the distance from the current price.
A snapshot of PYXS market posture derived from its technical indicators and recent volatility. Higher trend and alignment lean bullish; higher risk means larger swings.
Technical Analysis
Indicators computed on daily closing prices.
| Period | SMA | Action | EMA | Action |
|---|---|---|---|---|
| MA 5 | $1.85 | Sell | $1.83 | Sell |
| MA 10 | $2.03 | Sell | $1.95 | Sell |
| MA 20 | $2.08 | Sell | $1.99 | Sell |
| MA 50 | $1.78 | Sell | $1.88 | Sell |
| MA 100 | $1.65 | Buy | $1.91 | Sell |
| MA 200 | $2.25 | Sell | $2.00 | Sell |
| Name | Value | Action |
|---|---|---|
| RSI (14) | 43.10 | Neutral |
| Stoch RSI (14) | 8.25 | Buy |
| CCI (20) | -75.19 | Neutral |
| Williams %R (14) | -91.07 | Info |
| MACD (12,26,9) | -0.09 | Sell |
| ROC (12) | -36.86 | Sell |
| Bollinger %B (20,2) | 0.26 | Neutral |
| Stochastic %K (14) | 8.93 | Buy |
| TRIX (15) | 0.87 | Buy |
| Awesome (5,34) | -0.08 | Sell |
| Ultimate (7,14,28) | 30.07 | Neutral |
| Momentum (10) | -0.87 | Sell |
| Aroon Osc (25) | -40.00 | Sell |
| Hull MA (9) | 1.71 | Buy |
| ADX (14) | 18.48 | Neutral |
| ATR (14) | 0.13 | Info |
The near-term technical picture is bearish. RSI(14) is 40, and the price action is constrained around a short-term range. The stock’s 50-day simple moving average sits at $1.78, while the 200-day simple moving average is at $2.25, indicating near-term weakness relative to longer-term trend levels.
| Year | Min | Avg | Max | ROI | Sentiment |
|---|---|---|---|---|---|
| $1.15 | $1.73 | $2.71 | 0% | Neutral | |
| $1.17 | $1.62 | $2.44 | -6% | Neutral | |
| $1.18 | $1.73 | $2.77 | 0% | Neutral | |
| $1.42 | $2.20 | $3.69 | +27% | Bullish | |
| $1.52 | $2.47 | $4.31 | +43% | Bullish | |
| $1.93 | $3.28 | $5.92 | +90% | Bullish | |
| $1.99 | $3.52 | $6.55 | +104% | Bullish | |
| $1.75 | $3.24 | $6.18 | +87% | Bullish | |
| $1.81 | $3.47 | $6.79 | +101% | Bullish | |
| $1.58 | $3.15 | $6.30 | +82% | Bullish | |
| $2.41 | $5.35 | $11.76 | +209% | Bullish | |
| $6.34 | $14.09 | $32.41 | +714% | Bullish |
Current year — the forecast is anchored to the live price, so ROI shows 0%.
| Month | Min | Avg | Max | Change |
|---|---|---|---|---|
| May 2026 | $1.15 | $1.73 | $2.05 | +0.00% |
| June 2026 | $1.39 | $1.66 | $2.07 | -3.83% |
| July 2026 | $1.41 | $1.72 | $2.20 | +3.62% |
| August 2026 | $1.52 | $1.88 | $2.45 | +9.26% |
| September 2026 | $1.52 | $1.90 | $2.51 | +1.05% |
| October 2026 | $1.48 | $1.87 | $2.50 | -1.99% |
| November 2026 | $1.53 | $1.94 | $2.63 | +4.20% |
| December 2026 | $1.54 | $1.98 | $2.71 | +1.67% |
Click any year to see its month-by-month PYXS forecast. Min / Avg / Max are a bear / base / bull scenario; ROI is the projected move from the current price. Change is the month-over-month move in the average. Estimates, not guarantees.
By 2026, PYXS could reach as high as $2.71, with a base case around $1.73 and support toward $1.15 — roughly 0% from $1.73. A consolidation phase looks the most probable path here.
Expect PYXS to range from $1.17 to $2.44 through 2027. The $1.62 average target implies a -6% move from current prices. That is -6% versus the projected 2026 average. Price action looks broadly range-bound.
The PYXS price prediction for 2028 points to an average of $1.73 (low $1.18, high $2.77) — a potential gain of 0% on today's $1.73. A consolidation phase looks the most probable path here.
In 2029, PYXS is projected to trade between $1.42 and $3.69, averaging $2.20 — a potential gain of +27% from today's $1.73. That is up +27% on the projected 2028 average. Momentum favours further upside here.
Pyxis Oncology, Inc.'s 2030 outlook centres on $2.47, within a $1.52 to $4.31 range. That is up +12% on the projected 2029 average. That marks a +43% change versus current levels. Buyers look set to stay in control over this stretch.
By 2031, PYXS could reach as high as $5.92, with a base case around $3.28 and support toward $1.93 — roughly +90% from $1.73. Momentum favours further upside here.
Expect PYXS to range from $1.99 to $6.55 through 2032. The $3.52 average target implies a +104% move from current prices. That is up +7% on the projected 2031 average. Buyers look set to stay in control over this stretch.
The PYXS price prediction for 2033 points to an average of $3.24 (low $1.75, high $6.18) — a potential gain of +87% on today's $1.73. Momentum favours further upside here.
In 2034, PYXS is projected to trade between $1.81 and $6.79, averaging $3.47 — a potential gain of +101% from today's $1.73. That is up +7% on the projected 2033 average. Buyers look set to stay in control over this stretch.
Pyxis Oncology, Inc.'s 2035 outlook centres on $3.15, within a $1.58 to $6.30 range. That is -9% versus the projected 2034 average. That marks a +82% change versus current levels. Momentum favours further upside here.
By 2040, PYXS could reach as high as $11.76, with a base case around $5.35 and support toward $2.41 — roughly +209% from $1.73. Buyers look set to stay in control over this stretch.
Expect PYXS to range from $6.34 to $32.41 through 2050. The $14.09 average target implies a +714% move from current prices. That is up +163% on the projected 2040 average. Momentum favours further upside here.
Investing $1,000 in PYXS today (≈ 578.034682 PYXS) could be worth
$8,144.33
+$7,144.33 (+714%) by 2050 · US Dollar
Based on the average projected PYXS price of $14.09 in 2050.
Based on the base (average) forecast scenario. FX rates are indicative. Estimates only — not financial advice.
See what a past investment in PYXSwould be worth at today's price.
$1,000 invested in PYXS on May 27, 2025 (≈ 806.451607 PYXS) would be worth
$1,395.16
+$395.16 (+39.5%) today · 1.40× · US Dollar
Based on a PYXS entry price of $1.24 vs. today's $1.73.
| Invested | Entry price | Value today | Return |
|---|---|---|---|
| 1 week ago | $2 | $865 | -13.5% |
| 1 month ago | $1.76 | $982.95 | -1.7% |
| 3 months ago | $1.52 | $1,138.16 | +13.8% |
| 6 months ago | $5.19 | $333.33 | -66.7% |
| 1 year ago | $1.24 | $1,395.16 | +39.5% |
| All time (4.6y) ago | $13.2 | $131.06 | -86.9% |
Past performance from historical market data — it does not predict future results. FX rates are indicative. Not financial advice.
Enter a price to see how it sits against our PYXS forecast.
Our base-case forecast reaches $3.50 around 2032.
Implied market cap at $3.50: $221.74M
The multi-year forecast shows a shift from neutral in 2026 to bullish in later years, with 2026 (avg $1.73) through 2028 (avg $1.73) remaining near the current level, then rising through 2029 (avg $2.20), 2030 (avg $2.47), and continuing higher in subsequent years. The 2031–2032 period strengthens (2031 avg $3.28; 2032 avg $3.52) before a broader rise into 2033–2035. By 2040 the forecasted average is $5.35, and by 2050 it is $14.09, with corresponding ROI figures of 89.7, 103.6, 87.1, 100.5, and 81.9 across the 2031–2035 span, then 209.2 by 2040 and 714.4 by 2050.
These are estimates and not guarantees, reflecting potential upside as the company advances its clinical programs and partnerships.
Tap a question to reveal the answer.
In 2030 the forecasted average price is $2.47, with a min of $1.52 and a max of $4.31, and a projected ROI of 43.
Forecasts show a progression from neutral in 2026 to bullish in later years, with 2029 average $2.20, 2040 average $5.35, and 2050 average $14.09, but these are estimates and not guarantees.
The forecast allows the possibility of reaching higher levels over time, with 2050 average at $14.09 and a 2050 max of $32.41, though outcomes are not guaranteed.
Current price is $1.73 and market cap is $109.6M.
Bearish sentiment with RSI(14) at 40. The stock shows a 30-day range of $1.08 to $2.77, with a support level at $1.63 and a resistance level at $2.75.
Pyxis Oncology, Inc. Community Discussion
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