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Phio Pharmaceuticals Corp. is projected to rise to $1.26 by 2027, a +14% move from its current price of $1.10. PHIO is currently trading below its 50-day average (a bearish sign). Technical indicators currently lean sell.
A data-driven summary — not financial advice. See the full breakdown below.
Live market data via Yahoo Finance · updated 5/28/2026
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| May 29 | $1.07 | $1.10 | $1.13 | -0.01% |
| May 30 | $1.06 | $1.10 | $1.14 | -0.02% |
| May 31 | $1.05 | $1.10 | $1.15 | -0.02% |
| Jun 1 | $1.04 | $1.10 | $1.16 | -0.03% |
| Jun 2 | $1.04 | $1.10 | $1.17 | -0.04% |
| Jun 3 | $1.03 | $1.10 | $1.17 | -0.05% |
| Jun 4 | $1.02 | $1.10 | $1.18 | -0.06% |
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Week 1 | $1.02 | $1.10 | $1.18 | -0.06% |
| Week 2 | $0.9941 | $1.10 | $1.21 | -0.11% |
| Week 3 | $0.9714 | $1.10 | $1.24 | -0.17% |
| Week 4 | $0.9526 | $1.10 | $1.26 | -0.23% |
| Week 5 | $0.9363 | $1.10 | $1.28 | -0.29% |
| Week 6 | $0.9217 | $1.10 | $1.30 | -0.34% |
| Week 7 | $0.9085 | $1.10 | $1.32 | -0.40% |
Short-term targets derived from the forecast trend and recent volatility. Highly uncertain — not financial advice.
Phio Pharmaceuticals Corp. is a clinical stage biopharmaceutical company developing immuno-oncology therapies in the United States. It focuses on INTASYL compounds such as PH-762, designed to reduce the expression of PD-1 in multi-center Phase 1b dose-escalating clinical trials, and PH-894, intended to silence BRD4 in preclinical studies.
The company was formerly RXi Pharmaceuticals Corporation and changed its name to Phio Pharmaceuticals Corp. in November 2018. Phio was founded in 2003 and is based in King Of Prussia, Pennsylvania.
PHIO is currently priced at $1.09.
Its market capitalization is $12.66M and its market rank is 5090.
The overall price outlook is bullish over the long term, with the year-by-year forecast showing growth in average price from 2026 to 2050. Notable milestones include 2026 avg $1.09, 2028 avg $1.37, 2040 avg $2.34 and 2050 avg $4.01, with the max forecast rising to $7.36 by 2050.
A major floor 22.1% below — a decisive break under it would weaken the trend.
The nearest floor, 3.6% below — buyers have tended to step in here.
The nearest ceiling, 20.0% above — a clean break opens room to run.
A major ceiling 50.0% above — clearing it would confirm fresh momentum.
Key PHIO support and resistance from recent price action — levels where the trend has historically paused or reversed. Percentages are the distance from the current price.
A snapshot of PHIO market posture derived from its technical indicators and recent volatility. Higher trend and alignment lean bullish; higher risk means larger swings.
Technical Analysis
Indicators computed on daily closing prices.
| Period | SMA | Action | EMA | Action |
|---|---|---|---|---|
| MA 5 | $1.09 | Buy | $1.09 | Buy |
| MA 10 | $1.09 | Buy | $1.09 | Buy |
| MA 20 | $1.11 | Sell | $1.12 | Sell |
| MA 50 | $1.19 | Sell | $1.16 | Sell |
| MA 100 | $1.16 | Sell | $1.23 | Sell |
| MA 200 | $1.48 | Sell | $1.51 | Sell |
| Name | Value | Action |
|---|---|---|
| RSI (14) | 44.80 | Neutral |
| Stoch RSI (14) | 100.00 | Sell |
| CCI (20) | -25.82 | Neutral |
| Williams %R (14) | -50.00 | Info |
| MACD (12,26,9) | 0.00 | Buy |
| ROC (12) | 2.80 | Buy |
| Bollinger %B (20,2) | 0.42 | Neutral |
| Stochastic %K (14) | 50.00 | Neutral |
| TRIX (15) | -0.45 | Sell |
| Awesome (5,34) | -0.08 | Sell |
| Ultimate (7,14,28) | 55.19 | Neutral |
| Momentum (10) | 0.00 | Neutral |
| Aroon Osc (25) | -76.00 | Sell |
| Hull MA (9) | 1.09 | Buy |
| ADX (14) | 14.87 | Neutral |
| ATR (14) | 0.02 | Info |
Bearish sentiment currently surrounds the stock. The RSI(14) is 40, and the price trades below the SMA50 of $1.20 and the SMA200 of $1.49. Immediate support is at $1.06 and resistance at $1.32. The 30-day range spans from $0.9137 to $1.30. The stock exhibits high volatility, with annualized volatility around 50%.
| Year | Min | Avg | Max | ROI | Sentiment |
|---|---|---|---|---|---|
| $0.857 | $1.10 | $1.36 | 0% | Neutral | |
| $0.9998 | $1.26 | $1.68 | +14% | Neutral | |
| $1.08 | $1.39 | $1.92 | +26% | Bullish | |
| $1.12 | $1.48 | $2.10 | +35% | Bullish | |
| $1.05 | $1.42 | $2.06 | +29% | Bullish | |
| $1.01 | $1.38 | $2.04 | +25% | Bullish | |
| $1.09 | $1.53 | $2.31 | +39% | Bullish | |
| $1.08 | $1.53 | $2.35 | +39% | Bullish | |
| $1.23 | $1.76 | $2.75 | +60% | Bullish | |
| $1.41 | $2.06 | $3.26 | +87% | Bullish | |
| $1.56 | $2.43 | $4.09 | +121% | Bullish | |
| $2.41 | $4.20 | $7.71 | +282% | Bullish |
Current year — the forecast is anchored to the live price, so ROI shows 0%.
| Month | Min | Avg | Max | Change |
|---|---|---|---|---|
| May 2026 | $0.857 | $1.10 | $1.29 | +0.00% |
| June 2026 | $0.9224 | $1.08 | $1.30 | -1.57% |
| July 2026 | $0.9225 | $1.09 | $1.33 | +0.84% |
| August 2026 | $0.9442 | $1.12 | $1.38 | +3.02% |
| September 2026 | $0.9205 | $1.10 | $1.37 | -1.99% |
| October 2026 | $0.8781 | $1.06 | $1.32 | -4.14% |
| November 2026 | $0.88 | $1.06 | $1.34 | +0.65% |
| December 2026 | $0.8858 | $1.08 | $1.36 | +1.07% |
Click any year to see its month-by-month PHIO forecast. Min / Avg / Max are a bear / base / bull scenario; ROI is the projected move from the current price. Change is the month-over-month move in the average. Estimates, not guarantees.
By 2026, PHIO could reach as high as $1.36, with a base case around $1.10 and support toward $0.857 — roughly 0% from $1.10. A consolidation phase looks the most probable path here.
Expect PHIO to range from $0.9998 to $1.68 through 2027. The $1.26 average target implies a +14% move from current prices. That is up +14% on the projected 2026 average. Price action looks broadly range-bound.
The PHIO price prediction for 2028 points to an average of $1.39 (low $1.08, high $1.92) — a potential gain of +26% on today's $1.10. Buyers look set to stay in control over this stretch.
In 2029, PHIO is projected to trade between $1.12 and $2.10, averaging $1.48 — a potential gain of +35% from today's $1.10. That is up +7% on the projected 2028 average. Momentum favours further upside here.
Phio Pharmaceuticals Corp.'s 2030 outlook centres on $1.42, within a $1.05 to $2.06 range. That is -4% versus the projected 2029 average. That marks a +29% change versus current levels. Buyers look set to stay in control over this stretch.
By 2031, PHIO could reach as high as $2.04, with a base case around $1.38 and support toward $1.01 — roughly +25% from $1.10. Momentum favours further upside here.
Expect PHIO to range from $1.09 to $2.31 through 2032. The $1.53 average target implies a +39% move from current prices. That is up +11% on the projected 2031 average. Buyers look set to stay in control over this stretch.
The PHIO price prediction for 2033 points to an average of $1.53 (low $1.08, high $2.35) — a potential gain of +39% on today's $1.10. Momentum favours further upside here.
In 2034, PHIO is projected to trade between $1.23 and $2.75, averaging $1.76 — a potential gain of +60% from today's $1.10. That is up +15% on the projected 2033 average. Buyers look set to stay in control over this stretch.
Phio Pharmaceuticals Corp.'s 2035 outlook centres on $2.06, within a $1.41 to $3.26 range. That is up +17% on the projected 2034 average. That marks a +87% change versus current levels. Momentum favours further upside here.
By 2040, PHIO could reach as high as $4.09, with a base case around $2.43 and support toward $1.56 — roughly +121% from $1.10. Buyers look set to stay in control over this stretch.
Expect PHIO to range from $2.41 to $7.71 through 2050. The $4.20 average target implies a +282% move from current prices. That is up +73% on the projected 2040 average. Momentum favours further upside here.
Investing $1,000 in PHIO today (≈ 909.090909 PHIO) could be worth
$3,816.9
+$2,816.9 (+282%) by 2050 · US Dollar
Based on the average projected PHIO price of $4.2 in 2050.
Based on the base (average) forecast scenario. FX rates are indicative. Estimates only — not financial advice.
See what a past investment in PHIOwould be worth at today's price.
$1,000 invested in PHIO on May 27, 2025 (≈ 584.795309 PHIO) would be worth
$643.27
-$356.73 (-35.7%) today · 0.64× · US Dollar
Based on a PHIO entry price of $1.71 vs. today's $1.1.
| Invested | Entry price | Value today | Return |
|---|---|---|---|
| 1 week ago | $1.08 | $1,018.52 | +1.9% |
| 1 month ago | $1.21 | $909.09 | -9.1% |
| 3 months ago | $1.07 | $1,028.04 | +2.8% |
| 6 months ago | $1.26 | $873.02 | -12.7% |
| 1 year ago | $1.71 | $643.27 | -35.7% |
| All time (5.0y) ago | $238.9 | $4.6 | -99.5% |
Past performance from historical market data — it does not predict future results. FX rates are indicative. Not financial advice.
Enter a price to see how it sits against our PHIO forecast.
Our base-case forecast reaches $2.20 around 2040.
Implied market cap at $2.20: $25.56M
The multi-year forecast turns bullish from 2028 onward, with the average price rising to higher levels in subsequent years. Notable milestones include 2028 avg $1.37 with ROI 25.9%, 2029 avg $1.44 with ROI 32.5%, and 2030 avg $1.38 with ROI 26.8%. The outlook continues to strengthen through 2034 with avg $1.71 and ROI 56.9%, 2035 avg $1.99 and ROI 82.8%, and by 2040 avg $2.34 with ROI 115%.
By 2050 the average price is forecast at $4.01 with ROI 267.5%. These are estimates and carry uncertainty, but the trajectory suggests meaningful upside over the long term while acknowledging inherent risk in a clinical-stage equity.
Tap a question to reveal the answer.
Avg $1.38; min $1.03; max $2.01; ROI 26.8%.
Forecasts show neutral in 2026, then bullish from 2028 onward. Notable milestones include 2028 avg $1.37; 2040 avg $2.34; 2050 avg $4.01 with ROI up to 115% by 2040 and 267.5% by 2050.
Yes. The forecast max price reaches $7.36 by 2050.
Current price $1.09; Market cap $12.66M.
It changed its name to Phio Pharmaceuticals Corp. in November 2018.
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